The study focuses on the life satisfaction predictors investigating the predictive value of the CSE, work-family conflict (WFC), and work-family enrichment (WFE). Using a sample of 389 working adults (M=36.48., SD=9.002), which was divided into four groups based on sex and presence of children, results indicate the importance of CSE, WFC, and WFE as predictors for life satisfaction, CSE has been proven to moderate the relationship between job and life satisfaction, it has a predictive value in life satisfaction for working men (9.0%), employed fathers (14.9%), working women (71.2%), and employed mothers (10.8%). Other important predictors appear to be factors of job satisfaction: 1. nature of work, communication, and operating conditions for working men; 2. satisfaction with salary for employed fathers; 3. satisfaction with payment and fringe benefits among working women. Enrichment from family to work facilitates fulfilling life satisfaction in the group of employed fathers as well as employed mothers; enrichment from work to family contributes to life satisfaction among employed mothers. Self-efficacy appears to be important predictor of life satisfaction in the group of employed fathers.