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DOI Prefix 10.20431 |
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The Effect of Pyrroloquinoline Quinone (PQQ) on Viability of Human Colorectal Adenocarcinoma HT-29 Cell Line
Marcos Flores-Encarnacion1*, Itzel Cabrera-Aguilar1, Carlos Cabrera-Maldonado2, Rosa Maria Nava-Nolazco1
2. Depto. de Microbiologia. Facultad de Ciencias Quimicas. Benemerita Universidad Autonoma de Puebla.Puebla, Puebla, Mexico.
Citation :Marcos Flores-Encarnacion et.al., The Effect of Pyrroloquinoline Quinone (PQQ) on Viability of Human Colorectal Adenocarcinoma HT-29 Cell Line International Journal of Research Studies in Biosciences 2017,5(10) : 18-24.
The pyrroloquinoline quinone (PQQ) is a polyphenolic compound. It has been proposed as a new vitamin. PQQ was first recognized as a bacterial cofactor. Today, it is known more about the chemicalbiological properties of PQQ, especially of its beneficial impact on eukaryotic organisms. It has been reported that PQQ is a potent antioxidant and that it can function as a protector in cardiac lesions and others. The effect of PQQ on several cell lines also has been studied. The most relevant finding is that PQQ has induced apoptosis in cancer cells. This work shows some data about the effect of PQQ on the growth of human colorectal adenocarcinoma cell line HT-29.