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DOI Prefix 10.20431 |
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International Journal of Medicinal Plants and Natural Products
Volume-3 Issue-1, 2016, Page No:11-15
Phytochemical Screening, Chromatographic Studies and Antibacterial Activity of Carica Papaya Leaves Extracts
Abubakar Abdulhamid1,Isah Musa Fakai1,Ogar Joshua Ogwihi1
1.Department of Biochemistry, Kebbi State University of Science and Technology,PMB 1144, Aliero, Kebbi State, Nigeria.
Citation : Abubakar Abdulhamid,Isah Musa Fakai,Ogar Joshua Ogwihi, Phytochemical Screening, Chromatographic Studies and Antibacterial Activity of Carica Papaya Leaves Extracts International Journal of Medicinal Plants and Natural Products. 2016;3(1):11-15.
Abstract
The antibacterial activity of Carica papaya leaf extracts on pathogenic bacteria was observed in this study. Papaya leaves were extracted using water, methanol, chloroform and n-hexane as solvents. The C.Papaya leaves extracts were tested against Staphylococcus aureus, Bacillus subtillis, Salmonella typhi and Escherichia coli by agar well diffusion method. The extract demonstrated higher activities against tested bacteria with the highest activity (13 mm zone of inhibition) demonstrated against Escherichia coli. The methanol fraction was fractionated and yielded 7 fractions. The fraction 5 exhibited highest activity against E. coli. Preliminary phytochemical analysis showed that the extracts contain alkaloids, tannins, saponins and phenols. The results justified the use of Carica papaya leaf extracts in the treatment of gastroenteritis, uretritis, typhoid fever and wound infections
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