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DOI Prefix 10.20431 |
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International Journal of Medicinal Plants and Natural Products
Volume-1 Issue-1, 2015, Page No:40-43
Hematological and Clinical Changes in Rabbits Exposed to Cassia Senna
Sylvester.C.Ohadoma1*,Isaac.N.Nnatuanya2, Felix.N.Osuala3, Louis. U.Amazu1, Chris.E.Okolo1.
1.Department of Pharmacology, College of Medicine, Imo State University, Owerri, Nigeria
2.Department of Medical Laboratory Science, Madonna University, Elele, Nigeria
3.Department of Pharmacognosy, Faculty of Pharmacy, Madonna University, Elele, Nigeria
2.Department of Medical Laboratory Science, Madonna University, Elele, Nigeria
3.Department of Pharmacognosy, Faculty of Pharmacy, Madonna University, Elele, Nigeria
Citation : Sylvester.C.Ohadoma,et.al, Al-Zubaedi Raad Mahmood, Hematological and Clinical Changes in Rabbits Exposed to Cassia Senna International Journal of Medicinal Plants and Natural Products. 2015;1(1):40-43.
Abstract
Objectives: To asses the antifungal and wound healing effects of the leaf extracts of Mucuna pruriens. Material and Methods: The crude ethanol and aqueous extracts of the dried leaves obtained by 72h maceration in ethanol and water respectively were evaluated using modified agar-well diffusion method; and the wound healing activity by standard method, in which three groups comprising three mice each were used. Group 2 and 3 received 10% an 20% extract/petroleum jelly mixture respectively, while Gruop1 served as negative control and received only petroleum jelly. Results: The ethanol leaf extract showed more pronounced antifungal activity than the aqueous extract. Wounds treated with 10% and 20% extract petroleum jelly, showed compared to petroleum jelly only (control). Conclusion: The leaf extracts of M. pruriens exert antifungal effect and acceleration of wound healing process in albino mice.
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