Multicultural organizations are the hubs of various cultures hailing from across the world. Managing communication challenges in culturally diverse global teams is indeed a herculean task. Effective communication in multicultural organizations is similar to a human neural network; and once it fails the entire system gets dysfunctional. In a multicultural organization, communication is a powerful tool through which information is exchanged; trust is built; and constructive relationship is maintained. This paper primarily reviews the literatures on the concept of multicultural organizations. The second section deals with the available opportunities for communication in a multicultural set-up. The third part discusses the various dimensions of communication in a multicultural organization. The fourth section argues the possible challenges of communication in a multicultural organization. And, the final section proposes the ways, how multicultural organizations manage their communication challenges.