Treatments have been developed to prevent the spread of zebra mussel (Dreissena polymorpha) veligers during fish transportation, but the effects of these treatments on eggs have not been evaluated. This study examined rainbow trout (Oncorhynchus mykiss) egg survival after one of four chemical treatment regimens: 1. 100mg/L formalin for two hours, 2. potassium chloride at 750 mg/L for one hour followed by 20mg/L formalin for two hours, 3.potassium chloride at 750 mg/L for one hour followed by 20mg/L formalin for three hours, and 4. no chemical treatment (control). No significant differences in egg mortality were observed among the treatments. If needed to prevent the spread of zebra mussel veligers, any of the chemical treatments used in this study can be safely administered to eyed rainbow trout eggs.