Lactose intolerance diarrhoea and increasing threat of Organo toxicity due to increasing non dietary constituents in the food and drinks, even contamination of milk poses problems in diarrhoea management in spite of big antidiarrheal armamentarium.

In addition for the sake of convenience even injudicious combination of potent antimicrobials and antiprotozoal being used inspite of FDA warnings .Thus in the context the present study to evaluate the sugar free Norfloxacin and Sugar free Tinidazole suspension administered separately in therapeutic dose proves worth as compared to sugar based norfloxacin and Tinidazole suspension separately or in combination as Sugar free Tinidazole and Sugar free Norfloxacin administered separately every 12 hours achieves remission without any untoward effects ,drug related toxicity ,relapse ,recurrence and post therapeutic sequel even in neonates.