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  DOI Prefix   10.20431


 

International Journal of Advanced Research in Chemical Science
Volume 5, Issue 8, 2018, Page No: 1-4

In - Vitro Antioxidant Activity of Methanolic Extract of the Roots of Bergenia ciliate

Suman Lal Shrestha1, Suresh Awale2, Surya Kant Kalauni3*

1.Department of Chemistry Patan Multiple Campus, Patan, Lalitpur, Nepal
2.Division of Natural Drug Discovery, Institute of Natural Medicine, University of Toyama, Japan
3.Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal

Citation : Suman Lal Shrestha, Suresh Awale, Surya Kant Kalauni, In - Vitro Antioxidant Activity of Methanolic Extract of the Roots of Bergenia ciliate International Journal of Advanced Research in Chemical Science 2018, 5(8) : 1-4

Abstract

Bergenia ciliata is an important medicinal plant used in regions where western medicines are inaccessible due to their unavailability and high cost. The methanolic extract of Bergenia ciliataroots was screened for phytochemical constituents and in-vitro antioxidant activity. The plant extract showed the rich source of secondary metabolites that play the role for biological activities.The higher antioxidant activity of the plant is due to the presence of reactive constituents like phenols and flavonoids.The antioxidant activity of the plant extract was measured by DPPH free radical scavenging assay. In DPPH free radical scavenging assay the IC50 value of Bergenia ciliata was found to be 11.21μg/mL, while the IC50 value of standard ascorbic acid was found to be 45.93μg/mL


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