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DOI Prefix 10.20431 |
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International Journal of Advanced Research in Chemical Science
Volume-2 Issue-8, 2015, Page No:38-45
Application of I.R. Spectroscopy & Mass Spectrometry in Structural Elucidation of Drugs
Deepti Shikha (Asstt. Prof.)1*, Rita Awasthi (Reader)1
Department of Chemistry, Brahmanand P.G. College The Mall, Kanpur, UP (INDIA)
Citation : Deepti Shikha (Asstt. Prof.) & Rita Awasthi (Reader), Application of I.R. Spectroscopy & Mass Spectrometry in Structural Elucidation of Drugs International Journal of Advanced Research in Chemical Science. 2015;2(8):38-45.
Abstract
The use of IR and Mass spectroscopy in the R&D of natural drugs and pharmaceutical products has been reviewed highlighting the advantages of the techniques. IR spectroscopy has been applied to natural product composition analysis, product quality assessment and production control. Its disadvantages include the difficulty in quantification and interpreting the data, although recently developed instrumentation and computer algorithms have made this a lot easier. Mass spectrometry has both qualitative and quantitative uses. These include identifying unknown compounds, determining the isotopic composition of elements in a molecule, and determining the structure of a compound by observing its fragmentation.
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