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DOI Prefix 10.20431 |
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International Journal of Advanced Research in Chemical Science
Volume-2 Issue-11, 2015, Page No:27-33
Antimicrobial Activity Studies of Some Novel Propenones Bearing Arylfuran Moiety
Laxmana K.1, Suresh P. Nayak2, K. Sharath Chandra7, Jagadeesh Prasad D*3, Prakash Anil Castelino4, Kumara Chaluvaiah5, Prashantha Naik6
1.Department of Chemistry, Mangalore University Mangalagangothri, Karnataka
2.St Mary’s and Don Bosco Instituitions Shirva, Udupi, Karnataka
3.Department of Biosciences, Mangalore University Mangalagangothri, Karnataka
2.St Mary’s and Don Bosco Instituitions Shirva, Udupi, Karnataka
3.Department of Biosciences, Mangalore University Mangalagangothri, Karnataka
Citation : Laxmana K.,et.al, Antimicrobial Activity Studies of Some Novel Propenones Bearing Arylfuran Moiety International Journal of Advanced Research in Chemical Science. 2015;2(11):27-33.
Abstract
Novel series of Arylfuryl propenones (5a-l) were synthesized from substituted arylfurfural (3) and aromatic ketones (4) (Schemes 1 and 2). The newly synthesized compounds were confirmed and characterized by elemental analysis, FT-IR, 1H-NMR and Dart-Mass spectral data. They were also screened for their in vitro antibacterial and antifungal activities by Disc Diffusion Method The investigation of the antibacterial and antifungal screening studies revealed that the novel arylfuryl propenones (5a-l) possess substantial antimicrobial activity.
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