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DOI Prefix 10.20431 |
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International Journal of Advanced Research in Chemical Science
Volume-3 Issue-5, 2016, Page No: 37-43
Oxidation of Gabapentin by Potassium Ferrate (VI) in Alkaline Media-Kinetics and Mechanism Study
Hongru Liu1,Dan Wang2, Jinhuan Shan1*
College of Chemistry and Environmental Science, Hebei University, Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, 071 002 Hebei, China
Citation : Hongru Liu, Dan Wang, Jinhuan Shan, Oxidation of Gabapentin by Potassium Ferrate (VI) in Alkaline Media-Kinetics and Mechanism Study International Journal of Advanced Research in Chemical Science. 2016;3(5):37-43.
Abstract
In the present research, the reaction kinetics of Potassium Ferrate (VI) with gabapentin were studied by using spectrophotometer. The reaction was determined under alkaline condition at the different temperatures of 288.2K-308.2K. All data was obtained from the pseudo-first order reaction. It was found that the reaction is a first-order for reactant. The observed rates constants (kobs) increased with increasing [reductant], however, increasing [OH-], the kobs decreased. The reaction is negative fraction order with respect to [OH-]. The reasonable mechanism has been suggested to explain the experimental data. The rate constants of the rate-determining step and the thermodynamic activation parameters at 298.2K were calculated.
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