In the perspective to valorize Cameroonian castor bean (Ricinus communis L), physico-chemical properties of oil and cake from seeds of three accessions of this plant originated from the Sudano-sahelian and Sudano-guinean zones of Cameroon were assessed. Seeds oil extracted by soxhlet method using hexane exhibited contents varying significantly (p< 0.05) with the agroecological zone and castor bean accession. Seeds oil content ranged from 44.35 ± 0.22 to 53.65 ± 0.30 %. Nitrogen content of castor cake varied significantly (p< 0.05) from 1.80 ± 0.16 in Soudano-sahelian zone to 4.59 ± 0.30 g/100g DM in Sudano-Guinean zone. Potassium and phosphorus had mean values of 1.48 ± 0.25 and 0.13 ± 0.05 mg/100 g DM respectively. The most abundant fatty acid in the oil was ricinoleic acid with mean value range of 62-67 %. In conclusion Cameroonian Castor Oil may play a role in the chemical industry market while the cake may be useful in agriculture as biological fertilizer or as folder for animal nutrition, but it toxicity needs to be investigated.