G. diazotrophicus is a Gram negative and acid acetic bacterium that could be isolated from the roots, stems and leaves of sugarcane, and from the coffee plant, citrus fruits and others. This acetic acid bacterium has demonstrated beneficial effects in the cultures (use as biofertilizer) and it has been recognized for its nitrogen fixation ability, both as plant associated ands free-living bacteria. On the other hand, the acetic acid bacteria are microorganisms found in the environment that are also used in the food industry. However, in recent years reports have been raising concerns related to human bacteremia, endocarditis, and pneumonia, associated with acetic acid bacteria. In this work, we presents some evidence in relation to the possible pathogenic role of G. diazotrophicus due to the hemolytic capacity of this bacterium.