A Brief Notes on the Meaning of Induced Pluripotent Stem Cell
Mariam M. Gerges1, Heba N. Gad El-Hak 1*
Citation : Mariam M. Gerges, Heba N. Gad El-Hak, A Brief Notes on the Meaning of Induced Pluripotent Stem Cell International Journal of Research Studies in Zoology 2019, 5(1) : 14-17
Reprogramming technology surprised many cell biologists at the beginning. Induced pluripotent stem cell (IPSCs) caused a real evolution in the cell biology; cells can be reprogrammed into their embryonic states whenever you need. The techniques are evolved enormously fast and today there are tremendous investments to develop robust and sensitive ways to generate ideal pluripotent cells. However, for obtaining the pluripotent lines, their subsequent differentiation and characterization, validated techniques and reagents in order to achieve high quality and safe progenitor cells must be conducted under controlled conditions. While those processes are helping a lot to solve the biggest problem of medicine, they are also pushing minds to think more deeply about health and treatment of illness. Yet, iPSCs would have profound implications for both basic research and clinical therapeutics by providing a patient-specific model system to study the disease pathway and test the effectiveness of pharmacological agents, as well as by providing an ample source of autologous cells that could be used for transplantation. This review act as a small note for the student and researcher beginner in understanding the meaning of stem cell and induced pluripotent stem cells.